Hematological and Biological Markers of Neonatal Sepsis

نویسندگان

  • Ranjana Devi Khuraijam Dept. of Microbiology, Regional Institute of Medical Sciences, Imphal, India
چکیده مقاله:

  Septicemia in neonates is the commonest cause of mortality. Early recognition and diagnosis of neonatal sepsis remains a challenge because of the variable and nonspecific clinical presentation. The laboratory criteria are often non specific and not fully reliable. The objective of this review is to highlight the various hematological and biological markers of neonatal sepsis. We searched PubMed and Elsevier’s web of science from studies evaluating the hematological and biological markers of neonatal sepsis. The key words used were “neonatal sepsis”, “hematological marker” and ”biomarker”. Since a battery of markers of neonatal sepsis are available, it is always better to rely on a combination of markers along with the clinical correlation.  

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

hematological and biological markers of neonatal sepsis

septicemia in neonates is the commonest cause of mortality. early recognition and diagnosis of neonatal sepsis remains a challenge because of the variable and nonspecific clinical presentation. the laboratory criteria are often non specific and not fully reliable. the objective of this review is to highlight the various hematological and biological markers of neonatal sepsis. we searched pubmed...

متن کامل

New emerging biological markers of neonatal sepsis

| 2017 | 1 cell‐surface antigens are nonspecific biomarkers that have been extensively studied for the diagnosis and management of LONS. Serum amyloid A increases up to 1000‐fold in response to inflammation‐associated reactive amyloidosis. The utility of hepcidin as a regulator of inflammation for the diagnosis of late‐onset sepsis in very low birth weight infants was recently evaluated.[4] Isc...

متن کامل

Diagnostic Evaluation of Hematological Sepsis Score and Presepsin in Neonatal Sepsis

Background: Early detection of neonatal sepsis and categorization of patients based on clinical severity is not yet effectively achieved. Some hematological parameters are used to formulate a hematological scoring system (HSS) and a modified hematological scoring system (MHSS) to diagnose neonatal sepsis. A promising biomarker: Presepsin, or Soluble Cluster of Differentiation 14 SubType (sCD14-...

متن کامل

Hematological and Biochemical Predictors of Mortality in Neonatal Sepsis

Introduction: This study was conducted to study the factors predicting mortality in neonatal sepsis, so that focused attention is paid to them, with an aim to bring down the mortality rates in neonates admitted with sepsis. Methods: This study was a prospective observational study. Neonates who were admitted with a suspicion of sepsis or in whom sepsis was suspected anytime during hospital stay...

متن کامل

Hematological Scoring System for Early Diagnosis of Neonatal Sepsis

Background: To determine the accuracy of a simple and cost effective haematological scoring system (HSS) in the early diagnosis of neonatal sepsis using blood culture as a gold standard. Methods: In this prospective cross sectional study newborns (n=170) with history of prolonged rupture of membranes, maternal intrapartum fever > 1010 F or clinical signs of sepsis namely; neonatal fever ≥ 1010 ...

متن کامل

Neonatal Sepsis: An Update

Sepsis is the most common cause of neonatal mortality. As per National Neonatal-Perinatal Database (NNPD), 2002-2003, the incidence of neonatal sepsis in India was 30 per 1000 live births. Signs and symptoms of sepsis are nonspecific; therefore empirical antimicrobial therapy is promptly initiated after obtaining appropriate cultures. The early manifestations of neonatal sepsis are vague and il...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 8  شماره 3

صفحات  137- 146

تاریخ انتشار 2013-07-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023